![COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection | SpringerLink COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10096-020-04138-6/MediaObjects/10096_2020_4138_Fig2_HTML.png)
COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection | SpringerLink
![Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target | SpringerLink Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00134-020-05985-9/MediaObjects/134_2020_5985_Fig1_HTML.png)
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target | SpringerLink
![SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy](https://www.thno.org/v10/p7448/thnov10p7448g001.jpg)
SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
![What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID-19? The experts explain What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID-19? The experts explain](https://images.theconversation.com/files/334882/original/file-20200514-167762-9vl8um.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=1000&fit=clip)
What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID-19? The experts explain
![Frontiers | The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy Frontiers | The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy](https://www.frontiersin.org/files/Articles/753721/fcimb-11-753721-HTML/image_m/fcimb-11-753721-g001.jpg)
Frontiers | The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy
![Angiotensin II regulation of angiotensin‐converting enzymes in spontaneously hypertensive rat primary astrocyte cultures - Gowrisankar - 2016 - Journal of Neurochemistry - Wiley Online Library Angiotensin II regulation of angiotensin‐converting enzymes in spontaneously hypertensive rat primary astrocyte cultures - Gowrisankar - 2016 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/a1456a5d-20cf-4e29-8c89-babb88e182a3/jnc13641-fig-0005-m.jpg)
Angiotensin II regulation of angiotensin‐converting enzymes in spontaneously hypertensive rat primary astrocyte cultures - Gowrisankar - 2016 - Journal of Neurochemistry - Wiley Online Library
![ACE2 as a potential therapeutic target for pandemic COVID-19 - RSC Advances (RSC Publishing) DOI:10.1039/D0RA08228G ACE2 as a potential therapeutic target for pandemic COVID-19 - RSC Advances (RSC Publishing) DOI:10.1039/D0RA08228G](https://pubs.rsc.org/image/article/2020/RA/d0ra08228g/d0ra08228g-f1_hi-res.gif)
ACE2 as a potential therapeutic target for pandemic COVID-19 - RSC Advances (RSC Publishing) DOI:10.1039/D0RA08228G
![COVID-19 and ACE -inhibitors and angiotensin receptor blockers-: The need to differentiate between early infection and acute lung injury | Revista Colombiana de Cardiología COVID-19 and ACE -inhibitors and angiotensin receptor blockers-: The need to differentiate between early infection and acute lung injury | Revista Colombiana de Cardiología](https://multimedia.elsevier.es/PublicationsMultimediaV1/item/multimedia/S0120563320300772:gr1.jpeg?xkr=ue/ImdikoIMrsJoerZ+w997EogCnBdOOD93cPFbanNc1SMvz46gXX2zWoVNOOjrSljC3HaQAM0e2ci9vr0D6YcESMRhXHrGoUpQcnOUwut9xH6MzcRSZVEC59m1fAsmSZBwgwK8u1YAgwABUM09+BYp8dn4JXbz0B15JnY3mqSu+abGZ6aC0iaZUcyA6k0v+4Dufl440VCEO8BUXpRtjMXScUBvHz+MGgPWNzSJVa2tl3ZXazRSuuFUap0RjSHcPONwQg9ee4YwUOVwSNFmxcYnuD+lUPtU5LbitAcyVlCk=)
COVID-19 and ACE -inhibitors and angiotensin receptor blockers-: The need to differentiate between early infection and acute lung injury | Revista Colombiana de Cardiología
Role of angiotensin-converting enzyme 2 in neurodegenerative diseases during the COVID-19 pandemic | Aging
![IJMS | Free Full-Text | Do Changes in ACE-2 Expression Affect SARS-CoV-2 Virulence and Related Complications: A Closer Look into Membrane-Bound and Soluble Forms IJMS | Free Full-Text | Do Changes in ACE-2 Expression Affect SARS-CoV-2 Virulence and Related Complications: A Closer Look into Membrane-Bound and Soluble Forms](https://www.mdpi.com/ijms/ijms-22-06703/article_deploy/html/images/ijms-22-06703-g001.png)
IJMS | Free Full-Text | Do Changes in ACE-2 Expression Affect SARS-CoV-2 Virulence and Related Complications: A Closer Look into Membrane-Bound and Soluble Forms
View of The regulation of ACE-2 in the heart and lungs | The Southwest Respiratory and Critical Care Chronicles
![Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID19 | Signal Transduction and Targeted Therapy Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID19 | Signal Transduction and Targeted Therapy](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41392-020-00374-6/MediaObjects/41392_2020_374_Fig1_HTML.png)
Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID19 | Signal Transduction and Targeted Therapy
![Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure | Circulation Research Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure | Circulation Research](https://www.ahajournals.org/cms/asset/8d1b070b-7bd0-43bd-bf8a-349b3c5496cb/1313fig01.jpg)
Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure | Circulation Research
![Downregulation of ACE2 induces overstimulation of the renin–angiotensin system in COVID-19: should we block the renin–angiotensin system? | Hypertension Research Downregulation of ACE2 induces overstimulation of the renin–angiotensin system in COVID-19: should we block the renin–angiotensin system? | Hypertension Research](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41440-020-0476-3/MediaObjects/41440_2020_476_Fig1_HTML.png)
Downregulation of ACE2 induces overstimulation of the renin–angiotensin system in COVID-19: should we block the renin–angiotensin system? | Hypertension Research
![Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications - ScienceDirect Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S002432052030655X-gr1.jpg)
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications - ScienceDirect
![ACE2 Nascence, trafficking, and SARS-CoV-2 pathogenesis: the saga continues | Human Genomics | Full Text ACE2 Nascence, trafficking, and SARS-CoV-2 pathogenesis: the saga continues | Human Genomics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs40246-021-00304-9/MediaObjects/40246_2021_304_Fig1_HTML.png)